Virginia hughes science writer

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Big problems with little particles? By Elinor Hughes9 April No comments There is a risk that poor toxicology studies could start undermining the success of nanomaterials, reports Elinor Hughes Nanomaterials have been on the scene for over 15 years and they are being applied in a variety of sectors including coatings, textiles, energy, security, IT, food, cosmetics and medicine.

Nanoparticles — particles in the 1—nm range — have unique properties compared to their larger counterparts such as the ability to squeeze into spaces inaccessible to larger particles. But with the research still in its infancy, their long-term effects on human health and the environment remain poorly understood.

Concerns have also been raised about the way nanomaterial toxicity data is reported. The end of the s saw considerable investment in new nanoscale materials thanks to their distinct properties. But, by creating these tiny particles, scientists were creating potential new ways for materials to interact with the human body and the environment.

They observed that the nanoparticles can have an impact on the protein misfolding associated with the diseases. Nevertheless, the link had made newspaper headlines. Krug recently published a review in Angewandte Chemie called Nanoparticle research — are we on the right track? In this he states that toxicology tests carried out on nanoparticles by researchers with no toxicology expertise are not fit for purpose.

He scoured medical, pharmaceutical, toxicological and biological papers for tests done on nanoparticle uptake via the skin, the gastrointestinal tract and the lungs and found that most have serious errors. What they are doing is testing how a nanomaterial that gets into the body causes a biological effect, which is important in terms of human health implications, but a true toxicity test identifies the lethal dose, an intermediate dose and the dose with no effect.

Krug revealed that there are examples of exposure studies in animals in which researchers have used grams of nanoparticles, which in many cases represents an overdose way above normal exposure levels.

One such study showed that cells treated with even a minor overdose of a nanomaterial in an in vitro test died because they were covered by agglomerated nanoparticles, which had cut off their nutrient and oxygen supplies.

Results like this could give a false impression of the toxicity of the nanoparticle in question, as the true dose that the human body would be exposed to is not used.

As Krug points out, if a human overdosed on common table salt, it would be fatal.

This is a situation that he has tried to rectify. Inas part of a European Commission funded project called Nanommune, Krug edited a handbook of standard procedures for nanoparticles testing that described ways to prepare nanomaterials for assays, how to prepare suspensions, how to do the toxicity assays and how to validate the toxicity assays.

So the same mistakes that were made 10 years ago are being repeated again and again. Companies need to be sure that the toxicity or safety of a product complies with regulations, as well as with internal policies and values, to maintain brand trust, explains Maynard.

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By taking examples of personalities such as Charlotte Bronte and Jane AustenWoolf explained the nature of women, their quest for independence and their struggle to achieve notable positions in literary fields and as artists. Virginia Woolf along with James JoyceT.

The plus side of this is that academics have the flexibility to develop novel practices that may be more appropriate. Nurkiewicz says that the first things he looks at when reviewing a paper are the toxicological tests and safety data.

Making sure everyone is on the same page in terms of sharing knowledge and getting the right equipment for tests takes money and this has been an problem.This novel, dedicated to Woolf's flame, Vita Sackville-West, is a hybrid: sort of a science-fiction novel, kind of a pseudo-biography.

This book blurs lines of genre and gender with cross-dressing zest. Get the latest science news and technology news, read tech reviews and more at ABC News.

The exhaustively reported BuzzFeed article by reporters Peter Aldhous, Azeen Ghorayshi, and Virginia Hughes details women’s claims of sexual misconduct against Krauss that extend back more than. Howard Hughes Medical Institute 84 reviews.

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Public profile badge. Include this LinkedIn profile on other regardbouddhiste.com: Life Science Connect Editor at . A recent blog post by Jenny Rohn observed that 'celebrated science bloggers are predominantly male', and points to the fact that across the various science blogging collectives – including our.